Miwa H and Era T. Tracing the destiny of mesenchymal stem cells from embryo to adult bone marrow and white adipose tissue via Pdgfrαexpression. Development, Jan 29;145(2)., 2018

 

Ito N, Katoh K, Kushige H, Saito Y, Umemoto T, Matsuzaki Y, Kiyonari H, Kobayashi D, Soga M, Era T, Araki N, Furuta Y, Suda T, Kida Y and Ohta K. Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency. Sci Rep. 8: 1634, 2018.

 

Yoshida T, Awaya T, Jonouchi T, Kimura R, Kimura S, Era T, Heike T and Sakurai H. A Skeletal Muscle Model of Infantile-onset Pompe Disease with Patient-specific iPS Cells. Sci Rep. 7: 13473, 2017.

 

Furukawa JI, Soga M, Okada K, Yokota I, Piao J, Irie T, Era T,and Shinohara Y. Impact of the Niemann-Pick c1 Gene Mutation on the Total Cellular Glycomics of CHO Cells. J Proteome Res. 16: 2802-2810, 2017.

 

Motoyama K, Nishiyama R, Maeda Y, Higashi T, Ishitsuka Y, Kondo Y, Irie T, Era T and Arima H. Synthesis of multi-lactose-appended β-cyclodextrin and its cholesterol-lowering effects in Niemann-Pick type C disease-like HepG2 cells. Beilstein J Org Chem. 13: 10-18, 2017.

 

Khodeer S and Era T. Identifying the Biphasic Role of Calcineurin/NFAT Signaling Enables Replacement of Sox2 in Somatic Cell Reprogramming. Stem Cells 35: 1162-1175, 2017.

 

Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A Tanaka A, Watanabe D, Morita M, Kaji R, Takuma H, Takamoka A, Kunath T, Wray S, Furuya H, Era T, Fijisawa T, Nishitoh H, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Ayaki T, Ito H, Takahashi R, Yamanaka S and Inoue H. iPS-based drug repositioning identifies Src/c-abl as a therapeutic target for ALS moter neurons. Sci Transl Med. 9: eaaf3962, 2017.

 

Masaki H, Kato-Itoh M, Takahashi Y, Umino A, Sato H, Ito K, Yanagida A, Nishimura T, Yamaguchi T, Hirabayashi M, Era T, Loh KM, Wu SM, Weissman IL, Nakauchi H. Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos. Cell Stem Cell 19: 587–592, 2016.

 

Motoyama K, Nishiyama R, Maeda Y, Higashi T, Kawaguchi Y, Futaki S, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H. Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells. Biol Pharm Bull. 39: 1823-1829, 2016.

 

Hamauchi S, Shichinohe H, Uchino H, Yamaguchi S, Nakayama N, Kazumata K, Osanai T, Abumiya T, Houkin K, Era T. Cellular Functions and Gene and Protein Expression Profiles in Endothelial Cells Derived from Moyamoya Disease-Specific iPS Cells. PLoS One. 11: e0163561, 2016.

 

Wang Z, Nakamura K, Jinnin M, Kudo H, Goto M, Era T, Kira T, Nakashima T, Fukushima S, Ihn H. Establishment and gene expression analysis of disease-derived induced pluripotent stem cells of scleroderma. J Dermatol Sci. 84: 186-196, 2016.

 

Kondo T, Funayama M, Miyake M, Tsukita K, Era T, Osaka H, Ayaki T, Takahashi R, Inoue H. Modeling Alexander disease with patient iPSCs reveals cellular and molecular pathology of astrocytes. Acta Neuropathol Commun. 4: 69, 2016.

 

Sato Y, Kobayashi H, Higuchi T, Shimada Y, Era T, Kimura S, Eto Y, Ida H, Ohashi T. Disease modeling and lentiviral gene transfer in patient-specific induced pluripotent stem cells from late-onset Pompe disease patient. Mol Ther Methods Clin Dev., 2: 15023, 2015.

 

Yonehara A, Tanaka Y, Kulkeaw K, Era T, Nakanishi Y, Sugiyama D. Aloe vera Extract Suppresses Proliferation of Neuroblastoma Cells In Vitro. Anticancer Res, 35: 4479-4485, 2015.

 

Miwa H, Era T. Generation and characterization of PDGFRα-GFPCreERT2 knock-In mouse line. Genesis, 53, 329-36, 2015.

 

Maeda Y, Motoyama K, Higashi T, Horikoshi Y, Takeo T, Nakagata N, Kurauchi Y, Katsuki H, Ishitsuka Y, Kondo Y, Irie T, Furuya H, Era T, Arima H. Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients. J Pharm Pharmacol. 67: 1133-42, 2015.

 

Motoyama K, Hirai Y, Nishiyama R, Maeda Y, Higashi T, Ishitsuka Y, Kondo Y, Irie T, Era T and Arima H. Cholesterol lowering effects of mono-lactose-appended β-cyclodextrin in Niemann-Pick type C disease-like HepG2 cells. Beilstein J Org Chem. 11: 2079-86, 2015.

 

Soga M, Ishitsuka Y, Hamasaki M, Yoneda K, Furuya H, Matsuo M, Ihn H, Fusaki N, Nakamura K, Nakagata N, Endo F, Irie T, Era T. HPGCD outperforms HPBCD as a potential treatment for Niemann-Pick disease type C during disease modeling with iPS cells. Stem Cells. 33:1075-88, 2015.

 

Huang GJ, Edwards A, Tsai CY, Lee YS, Peng L, Era T, Hirabayashi Y, Tsai CY, Nishikawa S, Iwakura Y, Chen SJ, Flint J. Ectopic Cerebellar Cell Migration Causes Maldevelopment of Purkinje Cells and Abnormal Motor Behaviour in Cxcr4 Null Mice. PLoS One. 9: e86471, 2014.

 

Fujie Y, Fusaki N, Katayama T, Hamasaki M, Soejima Y, Soga M, Ban H, Hasegawa M, Yamashita S, Kimura S, Suzuki S, Matsuzawa T, Akari H, Era T. New Type of Sendai Virus Vector Provides Transgene-Free iPS Cells Derived from Chimpanzee Blood. PLoS One, 9: e113052, 2014.

 

Isono K, Jono H, Ohya Y, Shiraki N, Yamazoe T, Sugasaki A, Era T, Fusaki N, Tasaki M, Ueda M, Shinriki S, Inomata Y, Kume S, Ando Y. Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells. Stem Cell Res. 12: 574-583, 2014.

 

Miwa H and Era T. Mesoderm Differentiation from hiPS Cells. Methods Mol Biol. 2014.

 

Yoshimura N, Motohashi T, Aoki H, Tezuka K, Watanabe N, Wakaoka T, Era T, Kunisada T. Dual origin of melanocytes defined by Sox1 expression and their region-specific distribution in mammalian skin. Dev. Growth Differ. 55: 270-281, 2013.

 

Tanaka A, Woltjen K, Miyake K, Hotta A, Ikeya M, Yamamoto T, Nishino T, Shoji E, Sehara-Fujisawa A, Manabe Y, Fujii N, Hanaoka K, Era T, Yamashita S, Isobe K, Kimura E, Sakurai H. Efficient and Reproducible Myogenic differentiation from human iPS cells: Prospects for Modeling Miyoshi Myopathy in vitro. PLos One 8: e61540, 2013.

 

Era T. Pluripotent stem cell as a source of mesenchymal stem cell. Inflamm Regen. 33: 19-28, 2013.

 

Aoki H, Hara A, Era T, Kunisada T, and Yamada Y. Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development 139: 667-677, 2012.

 

Kitagawa M, Takabe A, Ono Y, Imai T, Nakao K, Nishikawa SI and Era T. Phf14, a Novel Regulator of Mesenchyme Growth via Platelet-derived Growth Factor (PDGF) Receptor-α .J. Biol. Chem. 287: 27983-27996 , 2012.

 

Hamasaki M, Hashizume Y, Yamada Y, Katayama T, Hohjoh H, Fusaki N, Nakashima Y, Furuya H, Haga N and Era T. Pathogenic mutation of ALK2 inhibits induced pluripotent stem cell reprogramming and maintenance: mechanisms of reprogramming and strategy for drug identification. Stem Cells 30: 2437-2449, 2012.

 

Kitagawa M, Takabe A, Ono Y, Imai T, Nakao K, Nishikawa SI and Era T. Phf14, a Novel Regulator of Mesenchyme Growth via Platelet-derived Growth Factor (PDGF) Receptor- a . J. Biol. Chem. 287: 27983-27996, 2012.

 

Era T. Mesoderm cell development from ES cells. Methods Mol Biol. 636: 87-103, 2010.

 

Kitagawa M and Era T. Differentiation of mesodermal cells from pluripotent stem cells. Int J Hematol.91: 373-383, 2010.

Shimizu , N., Watanabe, H., Kubota, J., Wu, J., Saito, R., Yokoi,T., Era, T., Iwatsubo, T., Watanabe, T., Nishina, S., Azuma, N,, Katada, T. and Nishina, H. Pax6-5a promotes neuronal differentiation of murine embryonic stem cells. Biol Pharm Bull . 32: 999-1003, 2009.

 

Kinoshita, M., Era,T., Jakt, LM. and Nishikawa, S-I. The novel protein kinase Vlk is essential for stromal function of mesenchymal cells. Development 136: 2069-2079, 2009.

 

Satoh Y., Matsumura I., Tanaka H., Ezoe S., Fukushima K., Tokunaga M., Yasumi M., Shibayama H., Mizuki M., Era T., Okuda T. and Kanakura Y. AML1/runx1 works as a negative regulator of C-MPL in hematopoietic stem cells. J Biol Chem. 283, 30045-30056, 2008.

 

Era, T., Izumi, N., Hayashi, M., Nishikawa, S., Nishikawa, S-I.
Multiple mesoderm subsets give rise to endothelial cells whereas hematopoietic cells are differentiated only from a restricted subset in ES cell differentiation culture.
Stem Cells 26: 401-411, 2008. 

 

Izumi, N., Era, T., Akimaru, H., Yasunaga, M. and Nishikawa, S-I.
Dissecting the molecular hierarchy for mesendoderm differentiation through a combination of embryonic stem cell culture and RNA interference.
Stem Cells. 25: 1664-1674, 2007.

 

Takashima, Y., Era, T., Nakao, K., Kondo, S., Kasuga, M., Smith, AG. and Nishikawa, S-I. Neuroepithelial cells supply an initial transient wave of MSC differentiation.
Cell 129: 1377-1388, 2007. 

 

Nishikawa, S-I., Jakt, L. M. and Era, T. ES cell culture as a tool for developmental cell biology. Nature Rev. Mol. Cell Biol. 8: 502-507, 2007. 

 

Tanaka, Y., Era, T., Nishikawa, S-I. and Kawamata, S. Forced expression of Nanog in hematopoietic stem cells results in a gd T cell disorder.
Blood. 110: 107-115, 2007. 

 

Kometani, K., Aoki, M., Kawamata, S., Shinozuka, Y., Era, T., Taniwaki, M., Hattori, M. and Minato, N. Role of SPA-1 in phenotypes of chronic myelogenous leukemia induced by BCR-ABL-expressing hematopoietic progenitors in a mouse model.
Cancer Res. 66: 9967-9976, 2006. 

 

Kobayashi, K., Era, T., Takebe, A., Jakt, LM. and Nishikawa, S-I. ARID3B induces malignant transformation of MEF and is strongly associated with malignant neuroblastoma. Cancer Res. 66: 8331-8336, 2006. 

 

Takebe, A., Era, T., Okada, M., Jakt, LM., Kuroda, Y. and Nishikawa, S-I. Microarray analysis of PDGFR a + populations in ES cell differentiation culture identifies genes involved in differentiation of mesoderm and mesenchyme including ARID3b that is essential for development of embryonic mesenchymal cells.
Dev. Biol. 293: 25-37, 2006. 

 

Sakurai, H., Era, T., Jakt, LM., Okada, M., Nakai, S., Nishikawa, S. and Nishikawa, S-I. In vitro modeling of paraxial and lateral mesoderm differentiation reveals early reversibility. Stem Cells. 24: 575-586, 2006.

 

Yasunaga, M., Tada, S., Torikai-Nishikawa, S., Nakano, Y., Okada, M., Yakt, L.M., Nishikawa, S., Chiba , T., Era, T. and Nishikawa, S-I. Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells.
Nature Biotech. 23: 1542-1550, 2005. 

 

Tada, S., Era, T., Furusawa, C., Sakurai, H., Nishikawa, S., Kinoshita, M., Nakao, K., Chiba , T. and Nishikawa, S-I. Characterization of mesendoderm: diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture. Development. 132: 4363-4374, 2005. 

 

Ishiko, E., Matsumura, I., Ezoe, S., Gale, K., Ishiko, J., Satoh, Y., Tanaka, H., Shibayama, H., Mizuki M., Era, T., Enver, T., and Kanakura, Y. Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1. J. Biol. Chem. 280: 4929-4939, 2005.