Inter-University Research Network for Medical Research Center for High Depth Omics
Establishment and development of the foundation of international collaboration for advanced “High Depth Omics” research in medical embryology

■Overview of the Project

This project aims to construct a network of four domestic centers to accomplish High Depth Omics research designed to comprehend multi-levels of biological molecular information across genome to metabolites, thereby leading to global technological development, human resource development, and the establishment of research platforms. To facilitate Big data-driven sciences, The Medical Research Center for High Depth Omics was established in April 2022, as a facility affiliated to IMEG. The Medical Research Center for High Depth Omics aims to establish the foundation of international collaboration for High Depth Omics that cover gene expression, protein-protein interactions, epigenome and chromatin structure at the level of single cells and single molecules.

 

■Inter-University Network for High Depth Omics

Thanks to technological innovation such as the high-speed sequencer, the mass spectrometer and other equipment, a variety of omics research is now developing with growing speed, which allows us to conduct multi-level omics research even at the level of single cells and single molecules. However, a task towards the integrated comprehension of big data in biology has been required for deep understanding of biological phenomena. “High Depth Omics” is the comprehensive approach driven by big-data of multi-level omics.
The project aims to establish the world-leading and practical use of High Depth Omics research through the collaboration of four leading domestic research centers that have outstanding research experience and equipment. This network has special significance in advanced research and human resource development in medical embryology that aims for organ reconstruction from stem cells.

 

■Affiliated Research Institutes

Institute of Molecular Embryology and Genetics, Kumamoto University
Medical Institute of Bioregulation, Kyushu University
Medical Research Institute, Tokyo Medical and Dental University
Institute for Advanced Medical Sciences, Tokushima University

 

■Committee member of Medical Research Center for High Depth Omics

Kei-ichiro Ishiguro Medical Research Center for High Depth Omics, Director・Professor Dept. of Chromosome Biology
Hitoshi Niwa IMEG Director・Professor Dept. of Pluripotent Stem Cell Biology
Yusuke Ono Associate Professor Dept. of Muscle Development and Regeneration
Kenji Shimamura Professor Dept. of Brain Morphogenesis
Norifumi Shioda Associate Professor Dept. of Genomic Neurology
Shinjiro Hino Associate Professor Dept. of Medical Cell Biology
Yasuyuki Okawa Visiting Professor MIB, Kyushu University
Itoshi Nikaido Visiting Professor MRI Tokyo Medical and Dental University
Tatsuya Takemoto Visiting Professor IAMS Tokushima University