Division of Organogenesis
Department of Germline Development
Publications

Publications (present – 2001)

 

Google Scholar: https://scholar.google.co.jp/citations?user=w8jue18AAAAJ&hl=ja
ORCID: http://orcid.org/0000-0001-6506-9146
Researchmap: https://researchmap.jp/read0118144/

 

 

Formicola, N., Heim, M., Dufourt, J., Lancelot, A.-S., Nakamura, A., Lagha, M. and *Besse, F. Tyramine induces dynamic RNP granule remodeling and translation activation in the Drosophila brain. eLife e65742.
https://doi.org/10.7554/eLife.65742

 

*Tanaka, T., Tani, N. and *Nakamura, A. Receptor-mediated yolk uptake is required for oskar mRNA localization and cortical anchorage of germ plasm components in the Drosophila oocyte. PLOS Biol. 19, e3001183.
https://doi.org/10.1371/journal.pbio.3001183

 

Yamamoto, M., Suwa, Y., Sugiyama, K., Okashita, N., Tani, N., Kawaguchi, M., Matsubara, K., Nakamura, A. and *Seki Y. PRDM14-CtBP1/2-PRC2 complex regulates transcriptional repression during transition from primed to naïve pluripotency. J. Cell Sci. jcs240176.
https://doi.org/10.1242/jcs.240176

 

Kamiyama, T., Sun, W., Tani, N., Nakamura, A. and *Niwa, R. (2020). Poly(A) Binding Protein is required for nuclear localization of the ecdysteroidogenic transcription factor Molting defective in the prothoracic gland of Drosophila melanogaster. Front. Genet. 11, 636.
https://doi.org/10.3389/fgene.2020.00636

 

Koiwai, K., Inaba, K., Morohashi, K., Enya, S., Arai, R., Kojima, H., Okabe, T., Fujisawa, Y., Inoue, H., Yoshino, R., Hirokawa, T., Kato, K., Fukuzawa, K., Shimada-Niwa, Y., Nakamura, A., Yumoto, F., Senda, T. and *Niwa, R. (2020). An integrated approach to unravel a crucial structural property for the function of the insect steroidogenic Halloween protein Noppera-bo. J. Biol. Chem. 295, 7154-7167.
https://doi.org/10.1074/jbc.RA119.011463

 

*Asaoka, M., Hanyu-Nakamura, K., Nakamura, A. and *Kobayashi, S. (2019). Maternal Nanos inhibits Importin-α2/Pendulin–dependent nuclear import to prevent somatic gene expression in the Drosophila germline. PLOS Genet. 15, e1008090.

https://doi.org/10.1371/journal.pgen.1008090

 

Kina, H., Yoshitani, T., Hanyu-Nakamura, K. and *Nakamura, A. (2019). Rapid and Efficient generation of GFP-knocked-in Drosophila by the CRISPR-Cas9-mediated genome editing. Develop. Growth Differ. 61, 265-275.
doi: 10.1111/dgd.12607.
・The cover article of the issue.

・Young Investigator Paper Award 2020

 

Hanyu-Nakamura, K., Matsuda, K., Cohen, S. M. and *Nakamura, A. (2019). Pgc suppresses the zygotically-acting RNA decay pathway to protect germ plasm RNAs in the Drosophila embryo. Development dev.167056. 
doi: 10.1242/dev.167056.

 

*Kikuchi, K., Nakamura, A., Arata, M., Shi, D., Nakagawa, M., Tanaka, T., Uemura, T., Fujimori, T., Kikuchi, A., Uezu, A., Sakamoto, Y. and *Nakanishi, H. (2018). Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling. EMBO Rep. e45471.
doi: 10.15252/embr.201745471

 

Yamane, M., Ohtsuka, S., Matsuura, K., Nakamura, A., Okano, M. and *Niwa, H. (2018). Overlapping functions of Krüppel-like factor family members: targeting multiple transcription factors to maintain naïve pluripotency of mouse embryonic stem cells. Development 145, dev162404.
doi: 10.1242/dev.162404.
•Featured in the “Research Highlight” section of the issue.

 

*Niwa, H., Nakamura, A., Urata, M., Shirae-Kurabayashi, M., Kuraku, S. and Ohtsuka, S. (2016). The evolutionally-conserved function of group B1 Sox family members confers the unique role of Sox2 in mouse ES cells. BMC Evol. Biol. 16, 173.
doi: 10.1186/s12862-016-0755-4

 

Liu, G., Sanghavi, P., Bollinger, K. E., Perry, L., Marshall, B., Roon, P., Tanaka, T., Nakamura, A. and *Gonsalvez, G. B. (2015). Efficient endocytic uptake and maturation in Drosophila oocytes requires Dynamitin/p50. Genetics 201, 631-649. doi:10.1534/genetics.115.180018.

 

*Sano, H., Nakamura, A., Texada, M., Truman, J. W., Ishimoto, H., Kamikouchi, A., Nibu, Y., Kume, K., Ida, T. and Kojima, M. (2015). The nutrient-responsive hormone CCHamide-2 controls growth by regulating insulin-like peptides in the brain of Drosophila melanogaster. PLOS Genet. 11, e1005209.
doi: 10.1371/journal.pgen.1005209.

 

Kim, G., Pai, C.-I., Sato, K., Person, M. D., Nakamura, A. and *Macdonald, P. M. (2015). Region-specific activation of oskar mRNA translation by inhibition of Bruno-mediated repression. PLOS Genet. 11, e1004992.
doi: 10.1371/journal.pgen.1004992.

 

Tsai, Y. C., Chang, W., Liou, W., Lee, W. H., Chang, Y. W., Wang, P. Y., Tanaka, T., Nakamura, A. and *Pai, L. M. (2014). Endophilin B is required for the Drosophila oocyte to endocytose yolk downstream of Oskar. Development 141, 563-573.
doi: 10.1242/dev.097022.

 

Pradhan, S. J., Nesler, K. R., Rosen, S. F., Kato, Y., Nakamura, A., Ramaswami, M. and *Barbee, S. A. (2012). The conserved P body component HPat/Pat1 negatively regulates synaptic terminal growth at the larval Drosophila neuromuscular junction. J. Cell Sci. 125, 6105-6116.
doi: 10.1242/jcs.113043.

 

Kato, Y. and *Nakamura, A. (2012). Roles of cytoplasmic RNP granules in intracellular RNA localization and translational control in the Drosophila oocyte. Develop. Growth Differ. (review article) 54, 19-31.
doi: 10.1111/j.1440-169X.2011.01314.x.

 

*Tanaka, T. and *Nakamura, A. (2011). Oskar-induced endocytic activation and actin remodeling for anchorage of the Drosophila germ plasm. BioArchitecture (Perspective review article) 1, 122-126.
doi: 10.4161/bioa.1.3.17313.

 

*Shirae-Kurabayashi, M., Matsuda, K. and *Nakamura, A. (2011). Ci-Pem-1 localizes to the nucleus and represses somatic gene transcription in the germline of Ciona intestinalis embryos. Development 138, 2871-2881. 
doi: 10.1242/dev.058131.
•The cover article of the issue. 
•Featured in the “Highlight” section in Biology of Reproduction.

 

Tanaka, T, Kato, Y., Hanyu-Nakamura, K., Matsuda, K. and *Nakamura, A. (2011). Drosophila Mon2 couples Oskar-induced endocytosis with actin remodeling for cortical anchorage of the germ plasm. Development 138, 2523-2532. 
doi: 10.1242/dev.062208.
•Highlighted in the “In This Issue” section.
•Featured in the “Highlights” in Nature Cell Biology.

 

Yamada, K., Fuwa, T., Ayukawa, T., Tanaka, T., Nakamura, A., Baron, M. and *Matsuno, K. (2011). Roles of Drosophila Deltex in Notch receptor endocytic trafficking and activation. Genes Cells 16, 261-272. 
doi: 10.1111/j.1365-2443.2011.01488.x.

 

*Nakamura, A., Shirae-Kurabayashi, M. and Hanyu-Nakamura, K. (2010). Repression of early zygotic transcription in the germline. Curr. Opin. Cell Biol. (review article) 22, 709-714. 
doi: 10.1016/j.ceb.2010.08.012.

 

Abe, M., Setoguchi, Y., Tanaka, T., Awano, W., Takahashi, K., Ueda, R., Nakamura, A. and *Goto, S. (2009). Membrane protein localization-dependent regulation by PI3K(III) and Rabenosyn-5 in Drosophila wing cells. PLoS ONE 4, e7306.
doi: 10.1371/journal.pone.0007306.

 

*Nakamura, A. and *Seydoux, G. (2008). Less is more: specification of the germline by transcriptional repression. Development (review article) 135, 3817-3827.
doi: 10.1242/dev.022434.

 

Aratani, S., Kageyama, Y., Nakamura, A., Fujita, H., Fujii, R., Nishioka, K. and *Nakajima, T. (2008). MLE activates transcription via the minimal transactivation domain in Drosophila. Int. J. Mol. Med. 21, 469-476.
doi: 10.3892/ijmm.21.4.469.

 

Tanaka, T. and *Nakamura, A. (2008). The endocytic pathway acts downstream of oskar in Drosophila germ plasm assembly. Development 135, 1107-1117. 
doi: 10.1242/dev.017293.
•Highlighted in the “In This Issue” section. 
•Cited over 100 times (Google Scholar).

 

Hanyu-Nakamura, K., Sonobe-Nojima, H., Tanigawa, A., Lasko, P. and *Nakamura, A. (2008). Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells. Nature 451, 730-733.
doi: 10.1038/nature06498.
• Cited over 100 times (Google Scholar).

 

Barbee, S. A., Estes, P. S., Cziko, A.-M., Hillebrand, J., Luedeman, R. A., Coller, J. M., Johnson, N., Howlett, I. C., Geng, C., Ueda, R., Brand, A. H., Newbury, S. F., Wilhelm, J. E., Levine, R. B., *Nakamura, A., *Parker, R. and *Ramaswami, M. (*corresponding authors) (2006). Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P-bodies. Neuron 52, 997-1009.
doi:10.1016/j.neuron.2006.10.028.
•Cited over 300 times (Google Scholar).

 

*Shirae-Kurabayashi, M. , Nishikata, T., Takamura, K., Tanaka, K.J., Nakamoto, C. and *Nakamura, A. (2006). Dynamic redistribution of vasa homolog and exclusion of somatic cell determinants during germ cell specification in Ciona intestinalis. Development 133, 2683-2693. 
doi: 10.1242/dev.02446.
•Cover article of the issue. 
•Selected in the “In This Issue” section.

 

Sengoku, T., Nureki, O., Nakamura, A., Kobayashi, S. and *Yokoyama, S. (2006). Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. Cell 125, 287-300. 
doi:10.1016/j.cell.2006.01.054
•Selected for “Previews” section.
•Cited over 450 times (Google Scholar).

 

Boag, P. R., Nakamura, A. and *Blackwell, T. K. (2005). A conserved RNA-protein complex component involved in physiological germline apoptosis regulation in C. elegans. Development 132, 4975-4986. 
doi: 10.1242/dev.02060.
•Selected for “In This Issue” section. 
•Cited over 100 times (Google Scholar).

 

Hanyu-Nakamura, K., Kobayashi, S. and *Nakamura, A. (2004). Germ cell-autonomous Wunen2 is required for germline development in Drosophila embryos. Development 131, 4545-4553. 
doi: 10.1242/dev.01321.
•Selected for “In This Issue” section.

 

*Nakamura, A., Sato, K. and Hanyu-Nakamura, K. (2004). Drosophila Cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis. Dev. Cell 6, 69-78. 
doi:10.1016/S1534-5807(03)00400-3
•Highlighted in the “In Brief” in Nat Rev. Mol. Cell Biol.
•Cited over 300 times (Google Scholar).

 

Sengoku, T., Nureki, O., Dohmae, N., Takio, K., Nakamura, A. Kobayashi, S. and *Yokoyama, S. (2004). Crystallization and preliminary X-ray analysis of the helicase domains of Vasa complexed with RNA and an ATP analogue. Acta Cryst. D60, 320-322.
doi:10.1107/S0907444903025897.

 

Kawashima, T., Nakamura, A., Yasuda, K. and *Kageyama, Y. (2003). Dmaf, a novel member of Maf transcription factor family is expressed in somatic gonadal cells during embryonic development and gametogenesis in Drosophila. Gene Expr. Pat. 3, 663-667.
doi:10.1016/S1567-133X(03)00093-0.

 

Styhler, S., Nakamura, A. and *Lasko, P. (2002). VASA localization requires the SPRY-domain and SOCS-box containing protein, GUSTAVUS. Dev. Cell 3, 865-876.
doi:10.1016/S1534-5807(02)00361-1.

 

Inoue, B.S., Shimoda, M., Nishinokubi, I., Siomi, M., Okamura, M., Nakamura, A., Kobayashi, S., Ishida, N. and *Siomi, H. (2002). A role for the Drosophila fragile X-related gene in circadian output. Curr. Biol. 12, 1331-1335.
doi:10.1016/S0960-9822(02)01036-9.
•Cited over 100 times (Google Scholar).

 

Sano, H., Nakamura, A. and *Kobayashi, S. (2002). Identification of a transcriptional regulatory region for germline-specific expression of vasa in Drosophila melanogaster. Mech. Dev. 112, 129-139.
doi:10.1016/S0925-4773(01)00654-2.

 

Nakamura, A., Amikura, R., Hanyu, K. and *Kobayashi, S. (2001). Me31B silences translation of oocyte-localizing RNAs through the formation of cytoplasmic RNP complex during Drosophila oogenesis. Development 128, 3233-3242.
•Cited over 200 times (Google Scholar).

 

Amikura, R., Kashikawa, M., Nakamura, A. and *Kobayashi, S. (2001). Presence of mitochondria-type ribosomes outside mitochondria in germ plasm of Drosophila embryos. Proc. Natl. Acad. Sci. USA 98, 9133-9138.

 

 

Review Article

1. Kato, Y. and Nakamura, A. (2012). Roles of cytoplasmic RNP granules in intracellular RNA localization and translational control in the Drosophila oocyte. Develop. Growth Differ. 54, 19-31.

 

2. Tanaka, T.* and Nakamura, A. (2011). Oskar-induced endocytic activation and actin remodeling for anchorage of the Drosophila germ plasm. BioArchitecture 1, 122-126.

 

3. Nakamura, A., Shirae-Kurabayashi, M. and Hanyu-Nakamura, K. (2010). Repression of early zygotic transcription in the germline. Curr. Opin. Cell Biol. 22, 709-714.

 

4. Nakamura, A. and Seydoux, G. (2008). Less is more: specification of the germline by transcriptional repression. Development 135, 3817-3827.